Adapting the ABCDEF Bundle to Meet the Needs of Patients Requiring Prolonged Mechanical Ventilation in the Long-Term Acute Care Hospital Setting: Historical Perspectives and Practical Implications

Michele C. Balas; John W. Devlin; Avelino C. Verceles; Peter Morris; E. Wesley Ely

doi:10.1055/s-0035-1570361

Seminars in Respiratory and Critical Care Medicine, Table of Contents

Semin Respir Crit Care Med 2016; 37(01): 119-135
DOI: 10.1055/s-0035-1570361

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Adapting the ABCDEF Bundle to Meet the Needs of Patients Requiring Prolonged Mechanical Ventilation in the Long-Term Acute Care Hospital Setting: Historical Perspectives and Practical Implications

Michele C. Balas

¹Center of Excellence in Critical and Complex Care, Ohio State University College of Nursing, Columbus, Ohio

,

John W. Devlin

²Division of Pulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, Northeastern University School of Pharmacy, Boston, Massachusetts

,

Avelino C. Verceles

³Division of Pulmonary and Critical Care, University of Maryland School of Medicine, Baltimore Maryland

,

Peter Morris

⁴Division of Pulmonary, Critical Care, and Sleep Medicine, University of Kentucky, Lexington, Kentucky

,

E. Wesley Ely

⁵Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, Tennessee

⁶Geriatric Research, Education and Clinical Center (GRECC) Service, Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee

› Author Affiliations

Abstract

When robust clinical trials are lacking, clinicians are often forced to extrapolate safe and effective evidence-based interventions from one patient care setting to another. This article is about such an extrapolation from the intensive care unit (ICU) to the long-term acute care hospital (LTACH) setting. Chronic critical illness is an emerging, disabling, costly, and yet relatively silent epidemic that is central to both of these settings. The number of chronically critically ill patients requiring prolonged mechanical ventilation is expected to reach unprecedented levels over the next decade. Despite the prevalence, numerous distressing symptoms, and exceptionally poor outcomes associated with chronic critical illness, to date there is very limited scientific evidence available to guide the care and management of this exceptionally vulnerable population, particularly in LTACHs. Recent studies conducted in the traditional ICU setting suggest interprofessional, multicomponent strategies aimed at effectively assessing, preventing, and managing pain, agitation, delirium, and weakness, such as the ABCDEF bundle, may play an important role in the recovery of the chronically critically ill. This article reviews what is known about the chronically critically ill, provide readers with some important historical perspectives on the ABCDEF bundle, and address some controversies and practical implications of adopting the ABCDEF bundle into the everyday care of patients requiring prolonged mechanical ventilation in the LTACH setting. We believe developing new and better ways of addressing both the science and organizational aspects of managing the common and distressing symptoms associated with chronic critical illness and prolonged mechanical ventilation will ultimately improve the quality of life for the many patients and families admitted to LTACHs annually.

Keywords

ABCDEF bundle - chronic critical illness - long-term acute care hospital - pain - sedation - delirium

Full Text

References

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